9:30 - 12:30pm Workshop A
Ensuring Success for Promising Peptides: Overcoming Challenges in Formulation
Delve into the challenges hindering promising peptides from realizing their potential in formulation, bridging the gap between development bioavailabilities and the hurdles faced during human studies. Analyze the intricacies of rodent pharmacology, and in vitro tests to achieve a viable peptide API.
This workshop will gather experts to discuss:
• Analyzing the discrepancy between high bioavailabilities in development vs. single digit bioavailability seen during formulation and human study stages
• Understanding rodent pharmacology and key considerations to contextualize preclinical studies
• Optimizing in vitro tests, knowing the importance of larger animals, and achieving double-digit bioavailability in clinical translation
Workshop Leaders
- Michael Hellerstein
Head of Preclinical Development
Vaxxinity - Tina Xiong
Associate Principal Scientist, Oral Formulation Sciences
Formulation Sciences
13:30 - 16:30pm Workshop B
Harnessing Nanotechnology for Targeted Peptide Delivery
Understand the science behind nanoparticle formulation, exploring the advantages and mechanisms of these carriers. Equip your team with actionable strategies to achieve sub-200 nm sizes, overcoming chemistry limitations and optimize targeted peptide delivery.
This workshop will gather experts to discuss:
• Reviewing the advantages and mechanisms of nanoparticle carriers
• Size matters: Achieving sub-200 nm and overcoming chemistry limitations
• Optimizing beyond traditional milling approaches and the promise of liquid methods or electrospinning
Workshop Leaders
- Nitin Joshi, PhD
Assistant Professor
Harvard Medical School Brigham and Women's Hospital - Yuhan Lee
Co-Founder
AltrixBio
