Manuel Merz
Company: The Broad Institute of MIT & Harvard
Job title: Postdoctoral Fellow
Seminars:
Panel Discussion: Uncovering Innovations in Peptide Drug Delivery & Formulation for Improved Bioavailability 8:45 am
• Leveraging ligand-targeted drug delivery in diabetes, oncology and cardiovascular indications • Enhancing permeability through nanoscale drug carriers, ingestible injectables and more • Exploring recent innovations in oral peptide delivery for improved bioavailabilityRead more
day: Day One
Designing Inherently Bioavailable Peptides With a Combinatorial Screening Approach 3:00 pm
• Combining sequential cyclization and one-pot peptide acylation to create diverse cyclic peptide libraries • Screening cyclic peptides against disease targets, such as thrombin, allowing for multiple iterative cycles of library synthesis • Creating cyclic peptides with nanomolar affinities, ensuring high stability and demonstrating oral bioavailabilityRead more
day: Day One