Manuel Merz

Manuel Merz

Company: The Broad Institute of MIT & Harvard

Job title: Postdoctoral Fellow

Seminars:

Panel Discussion: Uncovering Innovations in Peptide Drug Delivery & Formulation for Improved Bioavailability 8:45 am

• Leveraging ligand-targeted drug delivery in diabetes, oncology and cardiovascular indications • Enhancing permeability through nanoscale drug carriers, ingestible injectables and more • Exploring recent innovations in oral peptide delivery for improved bioavailabilityRead more

day: Day One

Designing Inherently Bioavailable Peptides With a Combinatorial Screening Approach 3:00 pm

• Combining sequential cyclization and one-pot peptide acylation to create diverse cyclic peptide libraries • Screening cyclic peptides against disease targets, such as thrombin, allowing for multiple iterative cycles of library synthesis • Creating cyclic peptides with nanomolar affinities, ensuring high stability and demonstrating oral bioavailabilityRead more

day: Day One

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