Designing Inherently Bioavailable Peptides With a Combinatorial Screening Approach
Time: 3:00 pm
day: Day One
Details:
• Combining sequential cyclization and one-pot peptide acylation to create diverse cyclic peptide libraries
• Screening cyclic peptides against disease targets, such as thrombin, allowing for multiple iterative cycles of library synthesis
• Creating cyclic peptides with nanomolar affinities, ensuring high stability and demonstrating oral bioavailability
